Nature Biotechnology, Published online: 03 June 2025; doi:10.1038/s41587-025-02707-8
The ancestral protein of the CRISPR–Cas9 system — less than half the size of its famous descendant — is engineered into an effective DNA-targeting tool that can be delivered by AAV as an epigenome editor for in vivo gene silencing.
Nature Biotechnology, Published online: 03 June 2025; doi:10.1038/s41587-025-02707-8The ancestral protein of the CRISPR–Cas9 system — less than half the size of its famous descendant — is engineered into an effective DNA-targeting tool that can be delivered by AAV as an epigenome editor for in vivo gene silencing. Read More
