Nature Chemistry, Published online: 12 June 2025; doi:10.1038/s41557-025-01849-1
The functionalization of carbon–carbon bonds in amines remains an important challenge in organic synthesis. Now a borane-catalysed method has been developed that enables the insertion of alkynes into the alkyl C–C bonds of amines, providing a versatile approach for the ring expansion of cyclic amines and chain elongation of acyclic amines.
Nature Chemistry, Published online: 12 June 2025; doi:10.1038/s41557-025-01849-1The functionalization of carbon–carbon bonds in amines remains an important challenge in organic synthesis. Now a borane-catalysed method has been developed that enables the insertion of alkynes into the alkyl C–C bonds of amines, providing a versatile approach for the ring expansion of cyclic amines and chain elongation of acyclic amines. Read More
