Live-cell imaging with fluorogenic radical-trapping antioxidant probes reveals the onset and progression of ferroptosis

Nature Chemistry, Published online: 26 September 2025; doi:10.1038/s41557-025-01966-x

Spatiotemporal information on ferroptosis progression is highly desired to develop new therapies. Now, the development of organelle-targeting fluorogenic radical-trapping antioxidants has enabled dissection of the dynamic subcellular evolution of ferroptosis through real-time live-cell fluorescence imaging.

​Nature Chemistry, Published online: 26 September 2025; doi:10.1038/s41557-025-01966-xSpatiotemporal information on ferroptosis progression is highly desired to develop new therapies. Now, the development of organelle-targeting fluorogenic radical-trapping antioxidants has enabled dissection of the dynamic subcellular evolution of ferroptosis through real-time live-cell fluorescence imaging. Read More

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