Identification of Tumor‐Specific Surface Proteins Enables Quantification of Extracellular Vesicle Subtypes for Early Detection of Pancreatic Ductal Adenocarcinoma (Adv. Sci. 21/2025)

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Identification of Tumor-Specific Surface Proteins Enables Quantification of Extracellular Vesicle Subtypes for Early Detection of Pancreatic Ductal Adenocarcinoma (Adv. Sci. 21/2025)

Early Pancreatic Cancer Detection

Na Sun, Hsian-Rong Tseng, Yazhen Zhu, and colleagues have developed a simple, noninvasive test for early pancreatic cancer detection. Their approach uses click chemistry to capture extracellular vesicles (EVs) released by cancer cells. Once isolated, these cancer EVs are analyzed with a standard PCR machine to measure their mRNA content, providing a promising biomarker for pancreatic cancer. More details can be found in article number 2414982.

​Advanced Science, Volume 12, Issue 21, June 5, 2025. Read More

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