Nature Chemistry, Published online: 03 October 2025; doi:10.1038/s41557-025-01933-6
Stereoselective access to either E- or Z-cyclic alkenes remains a formidable challenge. Now it has been shown that Pd-catalysed formal cycloaddition can lead to the construction of 11-membered heterocyclic alkenes. Ligand-induced divergent catalysis gives controlled access to either E- or Z-trisubstituted cycloalkenes starting from common terminal alkene substrates.
Nature Chemistry, Published online: 03 October 2025; doi:10.1038/s41557-025-01933-6Stereoselective access to either E- or Z-cyclic alkenes remains a formidable challenge. Now it has been shown that Pd-catalysed formal cycloaddition can lead to the construction of 11-membered heterocyclic alkenes. Ligand-induced divergent catalysis gives controlled access to either E- or Z-trisubstituted cycloalkenes starting from common terminal alkene substrates. Read More
