Nature Reviews Chemistry, Published online: 25 November 2025; doi:10.1038/s41570-025-00770-y
Genomic therapy offers a promising strategy for addressing central nervous system disorders. This Review highlights recent advances in chemical strategies and delivery platforms, such as lipid nanoparticles, polymers and oligonucleotide conjugates, and it discusses future directions to improve the application of genomic therapy in brain disorders.
Nature Reviews Chemistry, Published online: 25 November 2025; doi:10.1038/s41570-025-00770-yGenomic therapy offers a promising strategy for addressing central nervous system disorders. This Review highlights recent advances in chemical strategies and delivery platforms, such as lipid nanoparticles, polymers and oligonucleotide conjugates, and it discusses future directions to improve the application of genomic therapy in brain disorders. Read More
